They are a direct swap, so you will be OK.
Without a TPMS, you will continuously have a warning message come up on your DIC. You can clear the message, but it will re-appear next time you start the car.
In some places, you may not pass your State's Safely Inspection. Best to have them installed, they are there to protect your life.
2010 Equinox LTZ<br />4 cyl, FWD, S/R<br />Cardinal Red/Black